Benedikt Ley Selected Research

Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)

2/2022	A fluorometric assay to determine the protective effect of glucose-6-phosphate dehydrogenase (G6PD) against a Plasmodium spp. infection in females heterozygous for the G6PD gene: proof of concept in Plasmodium falciparum.
1/2022	Variation in Glucose-6-Phosphate Dehydrogenase activity following acute malaria.
5/2021	Implementing radical cure diagnostics for malaria: user perspectives on G6PD testing in Bangladesh.
1/2021	Glucose-6-phosphate dehydrogenase activity in individuals with and without malaria: Analysis of clinical trial, cross-sectional and case-control data from Bangladesh.
12/2020	Diagnostic Practices and Treatment for P. vivax in the InterEthnic Therapeutic Encounter of South-Central Vietnam: A Mixed-Methods Study.
1/2020	Case Report: A Case of Primaquine-Induced Hemoglobinuria in Glucose-6-Phosphate Dehydrogenase Deficient Malaria Patient in Southeastern Bangladesh.
1/2020	Wide range of G6PD activities found among ethnic groups of the Chittagong Hill Tracts, Bangladesh.
1/2020	Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis.
12/2019	Performance of the Access Bio/CareStart rapid diagnostic test for the detection of glucose-6-phosphate dehydrogenase deficiency: A systematic review and meta-analysis.
1/2019	Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial.

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Benedikt Ley Research Topics

Disease

14	Malaria 02/2022 - 07/2010
14	Glucosephosphate Dehydrogenase Deficiency 02/2022 - 01/2016
13	Hemolysis 01/2022 - 01/2016
8	Vivax Malaria 01/2022 - 01/2016
7	Infections 02/2022 - 01/2016
6	Typhoid Fever (Typhoid) 10/2019 - 06/2010
2	Falciparum Malaria (Plasmodium falciparum Malaria) 05/2022 - 08/2010
2	Acute malaria 01/2022 - 01/2016
2	Body Weight (Weight, Body) 01/2022 - 01/2020
2	Cholera 11/2012 - 01/2012
1	Communicable Diseases (Infectious Diseases) 10/2020
1	Hemoglobinuria 01/2020

Drug/Important Bio-Agent (IBA)

19	Primaquine FDA Link 05/2022 - 09/2015
14	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 02/2022 - 11/2017
12	Pharmaceutical PreparationsIBA 01/2022 - 01/2013
4	Chloroquine (Aralen)FDA LinkGeneric 01/2020 - 01/2016
3	tafenoquineIBA 01/2022 - 01/2017
3	8-aminoquinolineIBA 05/2021 - 11/2017
3	EnzymesIBA 01/2021 - 01/2016
3	VaccinesIBA 06/2013 - 01/2012
2	piperaquineIBA 01/2022 - 01/2018
2	artenimol (dihydroartemisinin)IBA 01/2022 - 01/2018
2	Antimalarials (Antimalarial Agents)IBA 01/2019 - 01/2016
2	ArtesunateIBA 03/2018 - 08/2010
1	kamalaIBA 01/2021
1	hemozoinIBA 05/2020
1	BilirubinIBA 01/2020
1	Hemoglobins (Hemoglobin)IBA 01/2020
1	tartrate-sensitive acid phosphataseIBA 10/2019
1	pyrimethamine drug combination fanasil (Fansidar)FDA Link 03/2018
1	TabletsIBA 01/2018
1	artemisinin (artemisinine)IBA 01/2018
1	Glucose-6-PhosphateIBA 01/2017
1	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 01/2016
1	mesoglycanIBA 01/2013
1	Bacterial VaccinesIBA 01/2012
1	LipopolysaccharidesIBA 05/2011
1	Immunoglobulin M (IgM)IBA 05/2011
1	Azithromycin (Zithromax)FDA LinkGeneric 08/2010
1	RNA (Ribonucleic Acid)IBA 07/2010
1	Indicators and Reagents (Reagents)IBA 06/2010

Therapy/Procedure

1	Traditional Medicine (Folk Remedies) 10/2020
1	Therapeutics 08/2010